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Cruises Calling at Pearl Islands

45 upcoming cruises that stop at Pearl Islands, Panama. Updated regularly; always confirm with the cruise line.

Hanseatic Inspiration
Hapag-Lloyd Cruises
Colon → Valparaiso-Santiago
⚓ Calls 12 Nov 202618 nights12 portsDeparts 2026 Nov 09
View itinerary · 12 ports
18 days, one-way from Colon to Valparaiso-Santiago
  1. 09 Nov - 23:59Departing from Colon, Panama
  2. 10 NovPanama Canal
  3. 11 NovPlaya Muerto Panama, Darien National Park
  4. 12 NovPearl Islands Panama, Islas Perlas
  5. 15 NovIsla de la Plata Ecuador
  6. 16 NovPaita, Peru
  7. 17 NovHuaura Islands Peru
  8. 18 NovSalaverry-Trujillo, Peru
  9. 20 Nov 06:00 - 21 Nov 18:00Callao-Lima, Peru
  10. 22 Nov 07:00 - 14:00Pisco, Paracas-Puerto General San Martin, Peru
  11. 25 NovPan de Azucar Island Chile
  12. 27 Nov 06:00Arriving in Valparaiso-Santiago, Chile
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Price on request
Le Bellot
Ponant Cruises
Colon → Puntarenas
⚓ Calls 25 Nov - 19:30 20269 nights10 portsDeparts 2026 Nov 22
View itinerary · 10 ports
9 days, one-way from Colon to Puntarenas
  1. 22 Nov 16:00Departing from Colon, Panama
  2. 23 Nov 14:00 - 19:00San Blas Islands Panama
  3. 24 NovPanama Canal
  4. 25 Nov - 19:30Pearl Islands Panama, Islas Perlas
  5. 26 Nov 07:00 - 13:30Playa Muerto Panama, Darien National Park
  6. 27 Nov 08:30 - 16:00Coiba Island Panama
  7. 28 Novcoastal cruising
  8. 29 Nov 06:00 - 18:00Bahia Drake Costa Rica
  9. 30 Nov 06:00 - 14:00Curu Wildlife Reserve, Costa Rica
  10. 01 DecArriving in Puntarenas, Puerto Caldera, Costa Rica
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$9500from / pp
National Geographic Quest
Lindblad Expeditions Cruises
Puntarenas → Colon
⚓ Calls 04 Dec 20267 nights10 portsDeparts 2026 Nov 29
View itinerary · 10 ports
7 days, one-way from Puntarenas to Colon
  1. 29 NovDeparting from Puntarenas, Puerto Caldera, Costa Rica
  2. 30 NovGolfito, Costa Rica
  3. 01 DecGolfo Dulce, Costa Rica
  4. 02 DecHerradura, Los Suenos, Costa Rica
  5. 03 DecCoiba Island Panama
  6. 04 DecPearl Islands Panama, Islas Perlas
  7. 04 DecPanama Canal
  8. 05 DecGatun Lake Panama Canal
  9. 05 DecPanama Canal
  10. 06 DecArriving in Colon, Panama
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$6129from / pp
National Geographic Quest
Lindblad Expeditions Cruises
Colon → Panama City
⚓ Calls 09 Dec - 10 Dec 20267 nights6 portsDeparts 2026 Dec 06
View itinerary · 6 ports
7 days, one-way from Colon to Panama City
  1. 06 DecDeparting from Colon, Panama
  2. 07 DecPortobelo, Panama
  3. 07 Dec - 08 DecPanama Canal
  4. 09 Dec - 10 DecPearl Islands Panama, Islas Perlas
  5. 11 DecPlaya Muerto Panama, Darien National Park
  6. 13 DecArriving in Panama City, Fuerte Amador, Balboa
Find this cruise to book →
$5550from / pp
Le Bellot
Ponant Cruises
Puntarenas → Colon
⚓ Calls 14 Dec - 21:30 20269 nights10 portsDeparts 2026 Dec 08
View itinerary · 10 ports
9 days, one-way from Puntarenas to Colon
  1. 08 Dec 23:59Departing from Puntarenas, Puerto Caldera, Costa Rica
  2. 09 Dec 10:30 - 18:30Curu Wildlife Reserve, Costa Rica
  3. 10 Dec 06:00 - 18:00Bahia Drake Costa Rica
  4. 11 Deccoastal cruising
  5. 12 Dec 07:00 - 16:30Coiba Island Panama
  6. 13 Dec 12:00 - 17:30Playa Muerto Panama, Darien National Park
  7. 14 Dec - 21:30Pearl Islands Panama, Islas Perlas
  8. 15 DecPanama Canal
  9. 16 Dec 14:00 - 19:00San Blas Islands Panama
  10. 17 Dec 07:00Arriving in Colon, Panama
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$9010from / pp
National Geographic Quest
Lindblad Expeditions Cruises
Panama City → Colon
⚓ Calls 16 Dec 20267 nights7 portsDeparts 2026 Dec 13
View itinerary · 7 ports
7 days, one-way from Panama City to Colon
  1. 13 DecDeparting from Panama City, Fuerte Amador, Balboa
  2. 13 DecPanama Canal
  3. 15 DecPlaya Muerto Panama, Darien National Park
  4. 16 DecPearl Islands Panama, Islas Perlas
  5. 17 Dec - 18 DecPanama Canal
  6. 19 DecPortobelo, Panama
  7. 20 DecArriving in Colon, Panama
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$4650from / pp
Star Clipper
Star Clippers Cruises
Panama City → Puntarenas
⚓ Calls 20 Dec 20267 nights8 portsDeparts 2026 Dec 19
View itinerary · 8 ports
7 days, one-way from Panama City to Puntarenas
  1. 19 DecDeparting from Panama City, Fuerte Amador, Balboa
  2. 20 DecPearl Islands Panama, Islas Perlas
  3. 21 DecIsla Iguana Panama
  4. 22 DecCoiba Island Panama
  5. 23 DecGolfito, Costa Rica
  6. 24 DecQuepos, Costa Rica
  7. 25 DecTortuga Island Costa Rica
  8. 26 DecArriving in Puntarenas, Puerto Caldera, Costa Rica
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Price on request
Le Bellot
Ponant Cruises
Colon → Puntarenas
⚓ Calls 22 Dec - 19:30 20269 nights10 portsDeparts 2026 Dec 19
View itinerary · 10 ports
9 days, one-way from Colon to Puntarenas
  1. 19 Dec 16:00Departing from Colon, Panama
  2. 20 Dec 14:00 - 19:00San Blas Islands Panama
  3. 21 DecPanama Canal
  4. 22 Dec - 19:30Pearl Islands Panama, Islas Perlas
  5. 23 Dec 07:00 - 13:30Playa Muerto Panama, Darien National Park
  6. 24 Dec 08:30 - 16:00Coiba Island Panama
  7. 25 Deccoastal cruising
  8. 26 Dec 06:00 - 18:00Bahia Drake Costa Rica
  9. 27 Dec 06:00 - 14:00Curu Wildlife Reserve, Costa Rica
  10. 28 DecArriving in Puntarenas, Puerto Caldera, Costa Rica
Find this cruise to book →
$9500from / pp
Le Laperouse
Ponant Cruises
Colon → Puntarenas
⚓ Calls 23 Dec - 19:30 20269 nights10 portsDeparts 2026 Dec 20
View itinerary · 10 ports
9 days, one-way from Colon to Puntarenas
  1. 20 Dec 16:00Departing from Colon, Panama
  2. 21 Dec 14:00 - 19:00San Blas Islands Panama
  3. 22 DecPanama Canal
  4. 23 Dec - 19:30Pearl Islands Panama, Islas Perlas
  5. 24 Dec 07:00 - 13:30Playa Muerto Panama, Darien National Park
  6. 25 Dec 08:30 - 16:00Coiba Island Panama
  7. 26 Deccoastal cruising
  8. 27 Dec 06:00 - 18:00Bahia Drake Costa Rica
  9. 28 Dec 06:00 - 21:30Curu Wildlife Reserve, Costa Rica
  10. 29 Dec 00:30Arriving in Puntarenas, Puerto Caldera, Costa Rica
Find this cruise to book →
$9500from / pp
National Geographic Quest
Lindblad Expeditions Cruises
Puntarenas → Panama City
⚓ Calls 01 Jan 20277 nights11 portsDeparts 2026 Dec 27
View itinerary · 11 ports
7 days, one-way from Puntarenas to Panama City
  1. 27 DecDeparting from Puntarenas, Puerto Caldera, Costa Rica
  2. 28 DecGolfito, Costa Rica
  3. 29 DecGolfo Dulce, Costa Rica
  4. 30 DecHerradura, Los Suenos, Costa Rica
  5. 31 DecCoiba Island Panama
  6. 01 JanPearl Islands Panama, Islas Perlas
  7. 01 JanPanama Canal
  8. 02 JanGatun Lake Panama Canal
  9. 02 JanPanama Canal
  10. 03 JanColon, Panama
  11. 03 JanArriving in Panama City, Fuerte Amador, Balboa
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$9515from / pp
Le Bellot
Ponant Cruises
Puntarenas → Colon
⚓ Calls 10 Jan - 21:30 20279 nights10 portsDeparts 2027 Jan 04
View itinerary · 10 ports
9 days, one-way from Puntarenas to Colon
  1. 04 Jan 23:59Departing from Puntarenas, Puerto Caldera, Costa Rica
  2. 05 Jan 10:30 - 18:30Curu Wildlife Reserve, Costa Rica
  3. 06 Jan 06:00 - 18:00Bahia Drake Costa Rica
  4. 07 Jancoastal cruising
  5. 08 Jan 07:00 - 16:30Coiba Island Panama
  6. 09 Jan 12:00 - 17:30Playa Muerto Panama, Darien National Park
  7. 10 Jan - 21:30Pearl Islands Panama, Islas Perlas
  8. 11 JanPanama Canal
  9. 12 Jan 14:00 - 19:00San Blas Islands Panama
  10. 13 Jan 07:00Arriving in Colon, Panama
Find this cruise to book →
$9500from / pp
Le Laperouse
Ponant Cruises
Puntarenas → Colon
⚓ Calls 11 Jan - 21:30 20279 nights10 portsDeparts 2027 Jan 05
View itinerary · 10 ports
9 days, one-way from Puntarenas to Colon
  1. 05 Jan 23:59Departing from Puntarenas, Puerto Caldera, Costa Rica
  2. 06 Jan 10:30 - 18:30Curu Wildlife Reserve, Costa Rica
  3. 07 Jan 06:00 - 18:00Bahia Drake Costa Rica
  4. 08 Jancoastal cruising
  5. 09 Jan 07:00 - 16:30Coiba Island Panama
  6. 10 Jan 12:00 - 17:30Playa Muerto Panama, Darien National Park
  7. 11 Jan - 21:30Pearl Islands Panama, Islas Perlas
  8. 12 JanPanama Canal
  9. 13 Jan 14:00 - 19:00San Blas Islands Panama
  10. 14 Jan 07:00Arriving in Colon, Panama
Find this cruise to book →
$9500from / pp
Star Clipper
Star Clippers Cruises
Puntarenas → Panama City
⚓ Calls 15 Jan 20277 nights8 portsDeparts 2027 Jan 09
View itinerary · 8 ports
7 days, one-way from Puntarenas to Panama City
  1. 09 JanDeparting from Puntarenas, Puerto Caldera, Costa Rica
  2. 10 JanTortuga Island Costa Rica
  3. 11 JanQuepos, Costa Rica
  4. 12 JanGolfito, Costa Rica
  5. 13 JanIsla Parida Panama
  6. 14 JanIsla Iguana Panama
  7. 15 JanPearl Islands Panama, Islas Perlas
  8. 16 JanArriving in Panama City, Fuerte Amador, Balboa
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Price on request
National Geographic Quest
Lindblad Expeditions Cruises
Puntarenas → Colon
⚓ Calls 15 Jan 20277 nights10 portsDeparts 2027 Jan 10
View itinerary · 10 ports
7 days, one-way from Puntarenas to Colon
  1. 10 JanDeparting from Puntarenas, Puerto Caldera, Costa Rica
  2. 11 JanGolfito, Costa Rica
  3. 12 JanGolfo Dulce, Costa Rica
  4. 13 JanHerradura, Los Suenos, Costa Rica
  5. 14 JanCoiba Island Panama
  6. 15 JanPearl Islands Panama, Islas Perlas
  7. 15 JanPanama Canal
  8. 16 JanGatun Lake Panama Canal
  9. 16 JanPanama Canal
  10. 17 JanArriving in Colon, Panama
Find this cruise to book →
$7130from / pp
Le Bellot
Ponant Cruises
Colon → Puntarenas
⚓ Calls 18 Jan - 19:30 20279 nights10 portsDeparts 2027 Jan 15
View itinerary · 10 ports
9 days, one-way from Colon to Puntarenas
  1. 15 Jan 16:00Departing from Colon, Panama
  2. 16 Jan 14:00 - 19:00San Blas Islands Panama
  3. 17 JanPanama Canal
  4. 18 Jan - 19:30Pearl Islands Panama, Islas Perlas
  5. 19 Jan 07:00 - 13:30Playa Muerto Panama, Darien National Park
  6. 20 Jan 08:30 - 16:00Coiba Island Panama
  7. 21 Jancoastal cruising
  8. 22 Jan 06:00 - 18:00Bahia Drake Costa Rica
  9. 23 Jan 06:00 - 14:00Curu Wildlife Reserve, Costa Rica
  10. 24 JanArriving in Puntarenas, Puerto Caldera, Costa Rica
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$10954from / pp
National Geographic Quest
Lindblad Expeditions Cruises
Colon → Panama City
⚓ Calls 20 Jan 20274 nights7 portsDeparts 2027 Jan 17
View itinerary · 7 ports
4 days, one-way from Colon to Panama City
  1. 17 JanDeparting from Colon, Panama
  2. 18 JanPortobelo, Panama
  3. 18 JanPanama Canal
  4. 19 JanGatun Lake Panama Canal
  5. 19 JanPanama Canal
  6. 20 JanPearl Islands Panama, Islas Perlas
  7. 21 JanArriving in Panama City, Fuerte Amador, Balboa
Find this cruise to book →
$6121from / pp
National Geographic Quest
Lindblad Expeditions Cruises
flight → Panama City
⚓ Calls 20 Jan 20274 nights10 portsDeparts 2027 Jan 17
View itinerary · 10 ports
4 days, round-trip 8 Night Exploring Arenal Volcano Pearl Islands and the Panama Canal Cruise and Land Tour
  1. 17 Janflight
  2. 17 JanDeparting from Panama City, Fuerte Amador, Balboa
  3. 17 JanColon, Panama
  4. 18 JanPortobelo, Panama
  5. 18 JanPanama Canal
  6. 19 JanGatun Lake Panama Canal
  7. 19 JanPanama Canal
  8. 20 JanPearl Islands Panama, Islas Perlas
  9. 21 JanPanama City, Fuerte Amador, Balboa
  10. 21 JanArriving in Panama City, Fuerte Amador, Balboa
Find this cruise to book →
$6121from / pp
National Geographic Quest
Lindblad Expeditions Cruises
Panama City → Colon
⚓ Calls 22 Jan 20274 nights7 portsDeparts 2027 Jan 21
View itinerary · 7 ports
4 days, one-way from Panama City to Colon
  1. 21 JanDeparting from Panama City, Fuerte Amador, Balboa
  2. 22 JanPearl Islands Panama, Islas Perlas
  3. 22 JanPanama Canal
  4. 23 JanGatun Lake Panama Canal
  5. 23 JanPanama Canal
  6. 24 JanPortobelo, Panama
  7. 25 JanArriving in Colon, Panama
Find this cruise to book →
$6121from / pp
National Geographic Quest
Lindblad Expeditions Cruises
flight → Panama City
⚓ Calls 22 Jan 20274 nights9 portsDeparts 2027 Jan 21
View itinerary · 9 ports
4 days, round-trip 8 Night Exploring Arenal Volcano Pearl Islands and the Panama Canal Cruise and Land Tour
  1. 21 Janflight
  2. 21 JanDeparting from Panama City, Fuerte Amador, Balboa
  3. 22 JanPearl Islands Panama, Islas Perlas
  4. 22 JanPanama Canal
  5. 23 JanGatun Lake Panama Canal
  6. 23 JanPanama Canal
  7. 24 JanPortobelo, Panama
  8. 25 JanColon, Panama
  9. 25 JanArriving in Panama City, Fuerte Amador, Balboa
Find this cruise to book →
$6121from / pp
National Geographic Quest
Lindblad Expeditions Cruises
Colon → Panama City
⚓ Calls 28 Jan 20274 nights7 portsDeparts 2027 Jan 25
View itinerary · 7 ports
4 days, one-way from Colon to Panama City
  1. 25 JanDeparting from Colon, Panama
  2. 26 JanPortobelo, Panama
  3. 26 JanPanama Canal
  4. 27 JanGatun Lake Panama Canal
  5. 27 JanPanama Canal
  6. 28 JanPearl Islands Panama, Islas Perlas
  7. 29 JanArriving in Panama City, Fuerte Amador, Balboa
Find this cruise to book →
$6121from / pp
National Geographic Quest
Lindblad Expeditions Cruises
flight → Panama City
⚓ Calls 28 Jan 20274 nights10 portsDeparts 2027 Jan 25
View itinerary · 10 ports
4 days, round-trip 8 Night Exploring Arenal Volcano Pearl Islands and the Panama Canal Cruise and Land Tour
  1. 25 Janflight
  2. 25 JanDeparting from Panama City, Fuerte Amador, Balboa
  3. 25 JanColon, Panama
  4. 26 JanPortobelo, Panama
  5. 26 JanPanama Canal
  6. 27 JanGatun Lake Panama Canal
  7. 27 JanPanama Canal
  8. 28 JanPearl Islands Panama, Islas Perlas
  9. 29 JanPanama City, Fuerte Amador, Balboa
  10. 29 JanArriving in Panama City, Fuerte Amador, Balboa
Find this cruise to book →
$6121from / pp
National Geographic Quest
Lindblad Expeditions Cruises
Round-trip from Panama City
⚓ Calls 01 Feb 20277 nights9 portsDeparts 2027 Jan 29
View itinerary · 9 ports
7 days, round-trip 7 Night Panama Canal Pearl Islands and Darien Jungle Cruise
  1. 29 JanDeparting from Panama City, Fuerte Amador, Balboa
  2. 29 JanPanama City, Fuerte Amador, Balboa
  3. 29 JanPanama Canal
  4. 31 JanPlaya Muerto Panama, Darien National Park
  5. 01 FebPearl Islands Panama, Islas Perlas
  6. 02 Feb - 03 FebPanama Canal
  7. 04 FebPortobelo, Panama
  8. 05 FebColon, Panama
  9. 05 FebArriving in Panama City, Fuerte Amador, Balboa
Find this cruise to book →
$8474from / pp
National Geographic Quest
Lindblad Expeditions Cruises
Puntarenas → Colon
⚓ Calls 18 Feb 20277 nights10 portsDeparts 2027 Feb 13
View itinerary · 10 ports
7 days, one-way from Puntarenas to Colon
  1. 13 FebDeparting from Puntarenas, Puerto Caldera, Costa Rica
  2. 14 FebGolfito, Costa Rica
  3. 15 FebGolfo Dulce, Costa Rica
  4. 16 FebHerradura, Los Suenos, Costa Rica
  5. 17 FebCoiba Island Panama
  6. 18 FebPearl Islands Panama, Islas Perlas
  7. 18 FebPanama Canal
  8. 19 FebGatun Lake Panama Canal
  9. 19 FebPanama Canal
  10. 20 FebArriving in Colon, Panama
Find this cruise to book →
$7130from / pp
ms Europa
Hapag-Lloyd Cruises
Valparaiso-Santiago → San Francisco
⚓ Calls 28 Feb 12:00 - 20:00 202729 nights16 portsDeparts 2027 Feb 17
View itinerary · 16 ports
29 days, one-way from Valparaiso-Santiago to San Francisco
  1. 17 Feb 21:00Departing from Valparaiso-Santiago, Chile
  2. 21 Feb 07:00 - 19:00Pisco, Paracas-Puerto General San Martin, Peru
  3. 22 Feb 06:00 - 23 Feb 17:00Callao-Lima, Peru
  4. 24 Feb 13:00 - 19:00Salaverry-Trujillo, Peru
  5. 26 Feb 08:00 - 18:00Manta, Ecuador
  6. 28 Feb 12:00 - 20:00Pearl Islands Panama, Islas Perlas
  7. 01 Mar 07:00 - 18:00Panama City, Fuerte Amador, Balboa
  8. 03 Mar 07:00 - 19:00Quepos, Costa Rica
  9. 05 Mar 07:00 - 19:00Puerto Quetzal, Guatemala
  10. 07 Mar 08:00 - 14:00Huatulco, La Crucecita, Mexico Riviera
  11. 09 Mar 08:00 - 14:00Puerto Vallarta, Jalisco, Mexico Riviera
  12. 11 Mar 09:00 - 19:00Cabo San Lucas, Baja California Mexico
  13. 14 Mar 08:00 - 18:00San Diego, California
  14. 15 Mar 07:00 - 18:00Santa Barbara CA, California
  15. 17 Mar 12:00San Francisco, California
  16. 18 MarArriving in San Francisco, California
Find this cruise to book →
Price on request
National Geographic Quest
Lindblad Expeditions Cruises
Puntarenas → Panama City
⚓ Calls 04 Mar 20277 nights11 portsDeparts 2027 Feb 27
View itinerary · 11 ports
7 days, one-way from Puntarenas to Panama City
  1. 27 FebDeparting from Puntarenas, Puerto Caldera, Costa Rica
  2. 28 FebGolfito, Costa Rica
  3. 01 MarGolfo Dulce, Costa Rica
  4. 02 MarHerradura, Los Suenos, Costa Rica
  5. 03 MarCoiba Island Panama
  6. 04 MarPearl Islands Panama, Islas Perlas
  7. 04 MarPanama Canal
  8. 05 MarGatun Lake Panama Canal
  9. 05 MarPanama Canal
  10. 06 MarColon, Panama
  11. 06 MarArriving in Panama City, Fuerte Amador, Balboa
Find this cruise to book →
$6111from / pp
National Geographic Quest
Lindblad Expeditions Cruises
Puntarenas → Colon
⚓ Calls 18 Mar 20277 nights10 portsDeparts 2027 Mar 13
View itinerary · 10 ports
7 days, one-way from Puntarenas to Colon
  1. 13 MarDeparting from Puntarenas, Puerto Caldera, Costa Rica
  2. 14 MarGolfito, Costa Rica
  3. 15 MarGolfo Dulce, Costa Rica
  4. 16 MarHerradura, Los Suenos, Costa Rica
  5. 17 MarCoiba Island Panama
  6. 18 MarPearl Islands Panama, Islas Perlas
  7. 18 MarPanama Canal
  8. 19 MarGatun Lake Panama Canal
  9. 19 MarPanama Canal
  10. 20 MarArriving in Colon, Panama
Find this cruise to book →
$6349from / pp
Le Bellot
Ponant Cruises
Puntarenas → Colon
⚓ Calls 04 Apr - 21:30 20279 nights10 portsDeparts 2027 Mar 29
View itinerary · 10 ports
9 days, one-way from Puntarenas to Colon
  1. 29 Mar 23:59Departing from Puntarenas, Puerto Caldera, Costa Rica
  2. 30 Mar 10:30 - 18:30Curu Wildlife Reserve, Costa Rica
  3. 31 Mar 06:00 - 18:00Bahia Drake Costa Rica
  4. 01 Aprcoastal cruising
  5. 02 Apr 07:00 - 16:30Coiba Island Panama
  6. 03 Apr 12:00 - 17:30Playa Muerto Panama, Darien National Park
  7. 04 Apr - 21:30Pearl Islands Panama, Islas Perlas
  8. 05 AprPanama Canal
  9. 06 Apr 14:00 - 19:00San Blas Islands Panama
  10. 07 Apr 07:00Arriving in Colon, Panama
Find this cruise to book →
$10490from / pp
National Geographic Quest
Lindblad Expeditions Cruises
Panama City → Colon
⚓ Calls 08 Nov 20277 nights7 portsDeparts 2027 Nov 05
View itinerary · 7 ports
7 days, one-way from Panama City to Colon
  1. 05 NovDeparting from Panama City, Fuerte Amador, Balboa
  2. 05 NovPanama Canal
  3. 07 NovPlaya Muerto Panama, Darien National Park
  4. 08 NovPearl Islands Panama, Islas Perlas
  5. 09 Nov - 10 NovPanama Canal
  6. 11 NovPortobelo, Panama
  7. 12 NovArriving in Colon, Panama
Find this cruise to book →
$6150from / pp
National Geographic Quest
Lindblad Expeditions Cruises
Colon → Panama City
⚓ Calls 29 Nov 20274 nights7 portsDeparts 2027 Nov 26
View itinerary · 7 ports
4 days, one-way from Colon to Panama City
  1. 26 NovDeparting from Colon, Panama
  2. 27 NovPortobelo, Panama
  3. 27 NovPanama Canal
  4. 28 NovGatun Lake Panama Canal
  5. 28 NovPanama Canal
  6. 29 NovPearl Islands Panama, Islas Perlas
  7. 30 NovArriving in Panama City, Fuerte Amador, Balboa
Find this cruise to book →
$6168from / pp
National Geographic Quest
Lindblad Expeditions Cruises
flight → Panama City
⚓ Calls 29 Nov 20274 nights10 portsDeparts 2027 Nov 26
View itinerary · 10 ports
4 days, round-trip 8 Night Exploring Arenal Volcano Pearl Islands and the Panama Canal Cruise and Land Tour
  1. 26 Novflight
  2. 26 NovDeparting from Panama City, Fuerte Amador, Balboa
  3. 26 NovColon, Panama
  4. 27 NovPortobelo, Panama
  5. 27 NovPanama Canal
  6. 28 NovGatun Lake Panama Canal
  7. 28 NovPanama Canal
  8. 29 NovPearl Islands Panama, Islas Perlas
  9. 30 NovPanama City, Fuerte Amador, Balboa
  10. 30 NovArriving in Panama City, Fuerte Amador, Balboa
Find this cruise to book →
$6168from / pp
National Geographic Quest
Lindblad Expeditions Cruises
Panama City → Colon
⚓ Calls 01 Dec 20274 nights7 portsDeparts 2027 Nov 30
View itinerary · 7 ports
4 days, one-way from Panama City to Colon
  1. 30 NovDeparting from Panama City, Fuerte Amador, Balboa
  2. 01 DecPearl Islands Panama, Islas Perlas
  3. 01 DecPanama Canal
  4. 02 DecGatun Lake Panama Canal
  5. 02 DecPanama Canal
  6. 03 DecPortobelo, Panama
  7. 04 DecArriving in Colon, Panama
Find this cruise to book →
$6168from / pp
National Geographic Quest
Lindblad Expeditions Cruises
flight → Panama City
⚓ Calls 01 Dec 20274 nights9 portsDeparts 2027 Nov 30
View itinerary · 9 ports
4 days, round-trip 8 Night Exploring Arenal Volcano Pearl Islands and the Panama Canal Cruise and Land Tour
  1. 30 Novflight
  2. 30 NovDeparting from Panama City, Fuerte Amador, Balboa
  3. 01 DecPearl Islands Panama, Islas Perlas
  4. 01 DecPanama Canal
  5. 02 DecGatun Lake Panama Canal
  6. 02 DecPanama Canal
  7. 03 DecPortobelo, Panama
  8. 04 DecColon, Panama
  9. 04 DecArriving in Panama City, Fuerte Amador, Balboa
Find this cruise to book →
$6168from / pp
Le Bellot
Ponant Cruises
Colon → Puntarenas
⚓ Calls 02 Dec - 19:30 20279 nights10 portsDeparts 2027 Nov 29
View itinerary · 10 ports
9 days, one-way from Colon to Puntarenas
  1. 29 Nov 16:00Departing from Colon, Panama
  2. 30 Nov 14:00 - 19:00San Blas Islands Panama
  3. 01 DecPanama Canal
  4. 02 Dec - 19:30Pearl Islands Panama, Islas Perlas
  5. 03 Dec 07:00 - 13:30Playa Muerto Panama, Darien National Park
  6. 04 Dec 08:30 - 18:00Coiba Island Panama
  7. 05 Deccoastal cruising
  8. 06 Dec 06:00 - 18:00Bahia Drake Costa Rica
  9. 07 Dec 06:00 - 12:30Curu Wildlife Reserve, Costa Rica
  10. 08 DecArriving in Puntarenas, Puerto Caldera, Costa Rica
Find this cruise to book →
$7790from / pp
Le Bougainville
Ponant Cruises
Colon → Puntarenas
⚓ Calls 06 Dec - 19:30 20279 nights10 portsDeparts 2027 Dec 03
View itinerary · 10 ports
9 days, one-way from Colon to Puntarenas
  1. 03 Dec 16:00Departing from Colon, Panama
  2. 04 Dec 14:00 - 19:00San Blas Islands Panama
  3. 05 Dec - 18:00Panama Canal
  4. 06 Dec - 19:30Pearl Islands Panama, Islas Perlas
  5. 07 Dec 07:00 - 13:30Playa Muerto Panama, Darien National Park
  6. 08 Dec 08:30 - 18:00Coiba Island Panama
  7. 09 Deccoastal cruising
  8. 10 Dec 06:00 - 18:00Bahia Drake Costa Rica
  9. 11 Dec 06:00 - 14:00Curu Wildlife Reserve, Costa Rica
  10. 12 DecArriving in Puntarenas, Puerto Caldera, Costa Rica
Find this cruise to book →
$7790from / pp
Le Bellot
Ponant Cruises
Puntarenas → Colon
⚓ Calls 21 Dec - 21:30 20279 nights10 portsDeparts 2027 Dec 15
View itinerary · 10 ports
9 days, one-way from Puntarenas to Colon
  1. 15 Dec 23:59Departing from Puntarenas, Puerto Caldera, Costa Rica
  2. 16 Dec 10:30 - 18:30Curu Wildlife Reserve, Costa Rica
  3. 17 Dec 06:00 - 18:00Bahia Drake Costa Rica
  4. 18 Deccoastal cruising
  5. 19 Dec 07:00 - 16:30Coiba Island Panama
  6. 20 Dec 12:00 - 17:30Playa Muerto Panama, Darien National Park
  7. 21 Dec - 21:30Pearl Islands Panama, Islas Perlas
  8. 22 DecPanama Canal
  9. 23 Dec 14:00 - 19:00San Blas Islands Panama
  10. 24 Dec 07:00Arriving in Colon, Panama
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National Geographic Quest
Lindblad Expeditions Cruises
Puntarenas → Colon
⚓ Calls 21 Dec 20277 nights10 portsDeparts 2027 Dec 16
View itinerary · 10 ports
7 days, one-way from Puntarenas to Colon
  1. 16 DecDeparting from Puntarenas, Puerto Caldera, Costa Rica
  2. 17 DecGolfito, Costa Rica
  3. 18 DecGolfo Dulce, Costa Rica
  4. 19 DecHerradura, Los Suenos, Costa Rica
  5. 20 DecCoiba Island Panama
  6. 21 DecPearl Islands Panama, Islas Perlas
  7. 21 DecPanama Canal
  8. 22 DecGatun Lake Panama Canal
  9. 22 DecPanama Canal
  10. 23 DecArriving in Colon, Panama
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Le Bougainville
Ponant Cruises
Puntarenas → Colon
⚓ Calls 25 Dec - 21:30 20279 nights10 portsDeparts 2027 Dec 19
View itinerary · 10 ports
9 days, one-way from Puntarenas to Colon
  1. 19 Dec 23:59Departing from Puntarenas, Puerto Caldera, Costa Rica
  2. 20 Dec 10:30 - 18:30Curu Wildlife Reserve, Costa Rica
  3. 21 Dec 06:00 - 18:00Bahia Drake Costa Rica
  4. 22 Deccoastal cruising
  5. 23 Dec 07:00 - 16:30Coiba Island Panama
  6. 24 Dec 12:00 - 17:30Playa Muerto Panama, Darien National Park
  7. 25 Dec - 21:30Pearl Islands Panama, Islas Perlas
  8. 26 DecPanama Canal
  9. 27 Dec 14:00 - 19:00San Blas Islands Panama
  10. 28 Dec 07:00Arriving in Colon, Panama
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Le Bellot
Ponant Cruises
Colon → Puntarenas
⚓ Calls 29 Dec - 19:30 20279 nights10 portsDeparts 2027 Dec 26
View itinerary · 10 ports
9 days, one-way from Colon to Puntarenas
  1. 26 Dec 16:00Departing from Colon, Panama
  2. 27 Dec 14:00 - 19:00San Blas Islands Panama
  3. 28 DecPanama Canal
  4. 29 Dec - 19:30Pearl Islands Panama, Islas Perlas
  5. 30 Dec 07:00 - 13:30Playa Muerto Panama, Darien National Park
  6. 31 Dec 08:30 - 18:00Coiba Island Panama
  7. 01 Jancoastal cruising
  8. 02 Jan 06:00 - 18:00Bahia Drake Costa Rica
  9. 03 Jan 06:00 - 11:00Curu Wildlife Reserve, Costa Rica
  10. 04 JanArriving in Puntarenas, Puerto Caldera, Costa Rica
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$7790from / pp
National Geographic Quest
Lindblad Expeditions Cruises
Puntarenas → Panama City
⚓ Calls 04 Jan 20287 nights11 portsDeparts 2027 Dec 30
View itinerary · 11 ports
7 days, one-way from Puntarenas to Panama City
  1. 30 DecDeparting from Puntarenas, Puerto Caldera, Costa Rica
  2. 31 DecGolfito, Costa Rica
  3. 01 JanGolfo Dulce, Costa Rica
  4. 02 JanHerradura, Los Suenos, Costa Rica
  5. 03 JanCoiba Island Panama
  6. 04 JanPearl Islands Panama, Islas Perlas
  7. 04 JanPanama Canal
  8. 05 JanGatun Lake Panama Canal
  9. 05 JanPanama Canal
  10. 06 JanColon, Panama
  11. 06 JanArriving in Panama City, Fuerte Amador, Balboa
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Star Clipper
Star Clippers Cruises
Colon → Puntarenas
⚓ Calls 22 Jan 20289 nights10 portsDeparts 2028 Jan 20
View itinerary · 10 ports
9 days, one-way from Colon to Puntarenas
  1. 20 JanDeparting from Colon, Panama
  2. 21 JanPanama Canal
  3. 22 JanPearl Islands Panama, Islas Perlas
  4. 23 JanIsla Iguana Panama
  5. 24 JanCoiba Island Panama
  6. 25 JanIsla Parida Panama
  7. 26 JanGolfito, Costa Rica
  8. 27 JanQuepos, Costa Rica
  9. 28 JanTortuga Island Costa Rica
  10. 29 JanArriving in Puntarenas, Puerto Caldera, Costa Rica
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Price on request
National Geographic Quest
Lindblad Expeditions Cruises
Puntarenas → Colon
⚓ Calls 23 Jan 20287 nights10 portsDeparts 2028 Jan 18
View itinerary · 10 ports
7 days, one-way from Puntarenas to Colon
  1. 18 JanDeparting from Puntarenas, Puerto Caldera, Costa Rica
  2. 19 JanGolfito, Costa Rica
  3. 20 JanGolfo Dulce, Costa Rica
  4. 21 JanHerradura, Los Suenos, Costa Rica
  5. 22 JanCoiba Island Panama
  6. 23 JanPearl Islands Panama, Islas Perlas
  7. 23 JanPanama Canal
  8. 24 JanGatun Lake Panama Canal
  9. 24 JanPanama Canal
  10. 25 JanArriving in Colon, Panama
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Emerald Azzurra
Emerald Cruises
Bridgetown → Puntarenas
⚓ Calls 25 Jan 202824 nights26 portsDeparts 2028 Jan 07
View itinerary · 26 ports
24 days, one-way from Bridgetown to Puntarenas
  1. 07 JanDeparting from Bridgetown, Barbados
  2. 07 JanSpeightstown, Port St Charles, Barbados
  3. 08 JanSaint Vincent Island, Kingstown, Grenadines
  4. 09 JanBequia Island, Port Elizabeth, Grenadines
  5. 10 JanMayreau Island, Grenadines
  6. 11 JanUnion Island Grenadines, Ashton
  7. 12 JanTobago Cays, Grenadines
  8. 13 JanBridgetown, Barbados
  9. 14 JanBequia Island, Port Elizabeth, Grenadines
  10. 15 JanMayreau Island, Grenadines
  11. 17 JanKralendijk Bonaire, Netherlands Antilles
  12. 18 JanWillemstad Curacao, Netherlands Antilles
  13. 19 JanOranjestad Aruba, Netherlands Antilles
  14. 20 JanSanta Marta Colombia
  15. 21 JanCartagena Colombia
  16. 22 JanSan Blas Islands Panama
  17. 23 JanPanama Canal
  18. 24 JanPanama City, Fuerte Amador, Balboa
  19. 25 JanPearl Islands Panama, Islas Perlas
  20. 26 JanPlaya Muerto Panama, Darien National Park
  21. 27 JanCebaco Island Panama
  22. 28 JanGolfito, Costa Rica
  23. 29 JanQuepos, Costa Rica
  24. 30 JanCuru Wildlife Reserve, Costa Rica
  25. 30 JanTortuga Island Costa Rica
  26. 31 JanArriving in Puntarenas, Puerto Caldera, Costa Rica
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National Geographic Quest
Lindblad Expeditions Cruises
flight → Panama City
⚓ Calls 28 Jan 20284 nights10 portsDeparts 2028 Jan 25
View itinerary · 10 ports
4 days, round-trip 8 Night Exploring Arenal Volcano Pearl Islands and the Panama Canal Cruise and Land Tour
  1. 25 Janflight
  2. 25 JanDeparting from Panama City, Fuerte Amador, Balboa
  3. 25 JanColon, Panama
  4. 26 JanPortobelo, Panama
  5. 26 JanPanama Canal
  6. 27 JanGatun Lake Panama Canal
  7. 27 JanPanama Canal
  8. 28 JanPearl Islands Panama, Islas Perlas
  9. 29 JanPanama City, Fuerte Amador, Balboa
  10. 29 JanArriving in Panama City, Fuerte Amador, Balboa
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National Geographic Quest
Lindblad Expeditions Cruises
Colon → Panama City
⚓ Calls 28 Jan 20284 nights7 portsDeparts 2028 Jan 25
View itinerary · 7 ports
4 days, one-way from Colon to Panama City
  1. 25 JanDeparting from Colon, Panama
  2. 26 JanPortobelo, Panama
  3. 26 JanPanama Canal
  4. 27 JanGatun Lake Panama Canal
  5. 27 JanPanama Canal
  6. 28 JanPearl Islands Panama, Islas Perlas
  7. 29 JanArriving in Panama City, Fuerte Amador, Balboa
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$6853from / pp
National Geographic Quest
Lindblad Expeditions Cruises
Panama City → Colon
⚓ Calls 01 Feb 20287 nights7 portsDeparts 2028 Jan 29
View itinerary · 7 ports
7 days, one-way from Panama City to Colon
  1. 29 JanDeparting from Panama City, Fuerte Amador, Balboa
  2. 29 JanPanama Canal
  3. 31 JanPlaya Muerto Panama, Darien National Park
  4. 01 FebPearl Islands Panama, Islas Perlas
  5. 02 Feb - 03 FebPanama Canal
  6. 04 FebPortobelo, Panama
  7. 05 FebArriving in Colon, Panama
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$6150from / pp

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