Cruise Ports
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Cruises Calling at Cape Girardeau

17 upcoming cruises that stop at Cape Girardeau, Missouri, USA. Updated regularly; always confirm with the cruise line.

Viking Mississippi
Viking River Cruises
Memphis TN → Nashville TN
⚓ Calls 30 Oct 20265 nights5 portsDeparts 2026 Oct 28
$5799from / pp
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Viking Mississippi
Viking River Cruises
Nashville TN → Memphis TN
⚓ Calls 07 Nov 20265 nights5 portsDeparts 2026 Nov 04
$5499from / pp
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Viking Mississippi
Viking River Cruises
Memphis TN → Nashville TN
⚓ Calls 13 Nov 20265 nights5 portsDeparts 2026 Nov 11
$5299from / pp
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Viking Mississippi
Viking River Cruises
Nashville TN → Memphis TN
⚓ Calls 21 Nov 20265 nights5 portsDeparts 2026 Nov 18
$4799from / pp
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ACL American Melody
American Cruise Lines Cruises
New Orleans → Minneapolis-Saint Paul
⚓ Calls 15 Jun 202721 nights18 portsDeparts 2027 Jun 05
$15890from / pp
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ACL American Serenade
American Cruise Lines Cruises
New Orleans → Minneapolis-Saint Paul
⚓ Calls 22 Jun 202721 nights18 portsDeparts 2027 Jun 12
$15890from / pp
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Viking Mississippi
Viking River Cruises
New Orleans → Alton IL
⚓ Calls 17 Jul 202714 nights11 portsDeparts 2027 Jul 06
$9999from / pp
Check fares
Viking Mississippi
Viking River Cruises
New Orleans → Minneapolis-Saint Paul
⚓ Calls 17 Jul 202721 nights18 portsDeparts 2027 Jul 06
$15998from / pp
Check fares
Viking Mississippi
Viking River Cruises
New Orleans → Alton IL
⚓ Calls 21 Aug 202714 nights11 portsDeparts 2027 Aug 10
$9999from / pp
Check fares
Viking Mississippi
Viking River Cruises
New Orleans → Minneapolis-Saint Paul
⚓ Calls 21 Aug 202721 nights18 portsDeparts 2027 Aug 10
$16498from / pp
Check fares
ACL American Melody
American Cruise Lines Cruises
New Orleans → Minneapolis-Saint Paul
⚓ Calls 13 Jun 202821 nights18 portsDeparts 2028 Jun 03
$15890from / pp
Check fares
ACL American Serenade
American Cruise Lines Cruises
New Orleans → Minneapolis-Saint Paul
⚓ Calls 20 Jun 202821 nights18 portsDeparts 2028 Jun 10
$15890from / pp
Check fares
Viking Mississippi
Viking River Cruises
New Orleans → Alton IL
⚓ Calls 22 Jul 202814 nights11 portsDeparts 2028 Jul 11
$9999from / pp
Check fares
Viking Mississippi
Viking River Cruises
New Orleans → Minneapolis-Saint Paul
⚓ Calls 22 Jul 202821 nights18 portsDeparts 2028 Jul 11
$16998from / pp
Check fares
Viking Mississippi
Viking River Cruises
New Orleans → Alton IL
⚓ Calls 26 Aug 202814 nights11 portsDeparts 2028 Aug 15
$9999from / pp
Check fares
Viking Mississippi
Viking River Cruises
New Orleans → Minneapolis-Saint Paul
⚓ Calls 26 Aug 202821 nights18 portsDeparts 2028 Aug 15
$16998from / pp
Check fares
ACL American Melody
American Cruise Lines Cruises
New Orleans → Minneapolis-Saint Paul
⚓ Calls 19 Jun 202921 nights18 portsDeparts 2029 Jun 09
$15890from / pp
Check fares

Itineraries and prices change — always confirm with the cruise line before booking. Some links are affiliate links that may earn us a commission at no extra cost to you.